BMJ Open (Sep 2024)
Latin American Surgical Outcomes Study in Paediatrics (LASOS-Peds): study protocol and statistical analysis plan for a multicentre international observational cohort study
- Ludhmila Abrahão Hajjar,
- Bruce M Biccard,
- Clarisa Lauber,
- Faye Evans,
- Nivaldo Alonso,
- Alexandra Torborg,
- Alexandra Vieira,
- Vinícius Caldeira Quintão,
- Gabriel Soares de Sousa,
- Francesco Consonni,
- Samuel Rodrigues,
- Julia Proença,
- Ricardo Vieira Carlos,
- Marcella Clemente,
- Mariana Neville,
- Fernanda Leite,
- Cristiano Tonello,
- Annery Garcia-Marcinkiewicz,
- Rodrigo Guris,
- Jose Herrera,
- Ana Andersen,
- Lorena Schaigorodsky,
- Nanci Biondini,
- Ninón Cajas,
- Francisco Cruzat,
- Luis Ignacio Cortínez,
- Marisol Giraldo,
- Alioth Valle,
- Cristian Pozo,
- Ana Betancourt,
- Maria Alejandra Echeto,
- Alma Dominguez,
- Lina Sarmiento,
- Kenya González,
- Gesely Ábrego,
- Lorena Leguizamón,
- Leila Paula,
- Gabriela Lopez,
- Maria José Carmona
Affiliations
- Ludhmila Abrahão Hajjar
- Discipline of Clinical Emergencies and Intensive Care, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Bruce M Biccard
- Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa
- Clarisa Lauber
- Hospital Pediátrico Pereira Rossell, Montevideo, Uruguay
- Faye Evans
- Boston Children′s Hospital, Harvard Medical School, Boston, Massachusetts, USA
- Nivaldo Alonso
- Discipline of Plastic Surgery, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Alexandra Torborg
- Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
- Alexandra Vieira
- Academic Research Organization, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Vinícius Caldeira Quintão
- Academic Research Organization, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Gabriel Soares de Sousa
- Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Francesco Consonni
- Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Samuel Rodrigues
- Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Julia Proença
- Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Ricardo Vieira Carlos
- Instituto da Criança e do Adolescente, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- Marcella Clemente
- Serviços Médicos de Anestesia, Hospital Sírio-Libanês, São Paulo, Brazil
- Mariana Neville
- Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal do Estado de São Paulo, São Paulo, Brazil
- Fernanda Leite
- Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, São Paulo, Brazil
- Cristiano Tonello
- Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, São Paulo, Brazil
- Annery Garcia-Marcinkiewicz
- Children′s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Rodrigo Guris
- Children′s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Jose Herrera
- Texas Children′s Hospital, Baylor University College of Medicine, Houston, Texas, USA
- Ana Andersen
- Instituto Materno Infantil, Mendoza, Argentina
- Lorena Schaigorodsky
- Hospital Nacional de Pediatria Dr. J. P. Garrahan, Buenos Aires, Argentina
- Nanci Biondini
- Clínica y Maternidad Suizo Argentina, Buenos Aires, Argentina
- Ninón Cajas
- Clínica Los Andes, La Paz, Bolivia
- Francisco Cruzat
- División de Anestesiología, Pontificia Universidad Católica de Chile, Santiago, Chile
- Luis Ignacio Cortínez
- División de Anestesiología, Pontificia Universidad Católica de Chile, Santiago, Chile
- Marisol Giraldo
- Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
- Alioth Valle
- Hospital Pediátrico Universitario William Soler, La Habana, Cuba
- Cristian Pozo
- Hospital Metropolitano de Quito, Quito, Pichincha, Ecuador
- Ana Betancourt
- Hospital Roosevelt de Guatemala, Ciudad de Guatemala, Guatemala
- Maria Alejandra Echeto
- Hospital del Valle, San Pedro Sula, Honduras
- Alma Dominguez
- Hospital General Dr. Manuel Gea González, Ciudad de México, Mexico
- Lina Sarmiento
- Instituto Nacional de Pediatría, Ciudad de México, Mexico
- Kenya González
- Asociación Pro-Niños Quemados, Managua, Nicaragua
- Gesely Ábrego
- Hospital de Especialidades Pediátricas Omar Torrijos Herrera, Cuidad de Panamá, Panama
- Lorena Leguizamón
- Hospital Pediátrico Niños de Acosta Ñu, San Lorenzo, Central, Paraguay
- Leila Paula
- Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru
- Gabriela Lopez
- Hospital Pediátrico Pereira Rossell, Montevideo, Uruguay
- Maria José Carmona
- Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
- DOI
- https://doi.org/10.1136/bmjopen-2024-086350
- Journal volume & issue
-
Vol. 14,
no. 9
Abstract
Introduction Surgery is a cost-effective public health intervention. Access to safe surgery is a basic human right. However, there are still significant disparities in the access to and safety of surgical and anaesthesia care between low-income and middle-income countries and high-income countries. The Latin American Surgical Outcomes Study in Paediatrics (LASOS-Peds) is an international, observational, 14-day cohort study to investigate the incidence of 30-day in-hospital complications following elective or emergency paediatric surgery in Latin American countries.Methods and analysis LASOS-Peds is a prospective, international, multicentre observational study of paediatric patients undergoing both elective and non-elective surgeries and procedures, inpatient and outpatient, including those performed outside the operating room. The primary outcome is the incidence of in-hospital postoperative complications up to 30 days after surgery. Secondary outcomes include intraoperative complications and the need for intensive care unit admission.Ethics and dissemination This study received approval from the Institutional Review Board of the coordinating centre (Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo) as well as from all the participating centres. The study results are expected to be published in peer-reviewed journals and disseminated at international conferences.Trial registration number NCT05934682.