LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration

Abstract

Lymphoid progenitors migrate from the bone marrow into the thymus to give rise to T and NK cell lineages. Here the authors characterize a lymphotoxin receptor beta-dependent population of thymic endothelial cells that guide lymphoid progenitor homing in the thymus.