Sensors (Aug 2020)

An Acridine-Based Fluorescent Sensor for Monitoring ClO<sup>−</sup> in Water Samples and Zebrafish

  • Su Chan Lee,
  • Soyoung Park,
  • Haeri So,
  • Gyudong Lee,
  • Ki-Tae Kim,
  • Cheal Kim

DOI
https://doi.org/10.3390/s20174764
Journal volume & issue
Vol. 20, no. 17
p. 4764

Abstract

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A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.

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