Nature Communications (Nov 2019)
Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon
- Javier Espadas,
- Diana Pendin,
- Rebeca Bocanegra,
- Artur Escalada,
- Giulia Misticoni,
- Tatiana Trevisan,
- Ariana Velasco del Olmo,
- Aldo Montagna,
- Sergio Bova,
- Borja Ibarra,
- Peter I. Kuzmin,
- Pavel V. Bashkirov,
- Anna V. Shnyrova,
- Vadim A. Frolov,
- Andrea Daga
Affiliations
- Javier Espadas
- Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular, Biology, University of the Basque Country
- Diana Pendin
- Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini
- Rebeca Bocanegra
- IMDEA Nanociencia, C/Faraday 9, Ciudad Universitaria de Cantoblanco
- Artur Escalada
- Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular, Biology, University of the Basque Country
- Giulia Misticoni
- Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini
- Tatiana Trevisan
- Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini
- Ariana Velasco del Olmo
- Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular, Biology, University of the Basque Country
- Aldo Montagna
- Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini
- Sergio Bova
- Department of Pharmaceutical and Pharmacological Sciences, University of Padova
- Borja Ibarra
- IMDEA Nanociencia, C/Faraday 9, Ciudad Universitaria de Cantoblanco
- Peter I. Kuzmin
- A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
- Pavel V. Bashkirov
- Federal Research and Clinical Centre of Physical-Chemical Medicine
- Anna V. Shnyrova
- Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular, Biology, University of the Basque Country
- Vadim A. Frolov
- Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular, Biology, University of the Basque Country
- Andrea Daga
- Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini
- DOI
- https://doi.org/10.1038/s41467-019-13327-7
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 11
Abstract
The endoplasmic reticulum (ER) is an intracellular network characterized by highly dynamic behavior whose control mechanisms are unclear. Here, the authors show that the ER-membrane protein Reticulon (Rtnl1) can constrict ER bilayers and lead to ER fission.
