Разработка и регистрация лекарственных средств (Jan 2019)

BRONCHODILATOR AND TOCOLYTIC FEATURES OF β<sub>2</sub>-ADRENOCEPTOR AGONISTS

  • S. Ya. Skachilova,
  • E. V. Shilova,
  • V. M. Pavlov,
  • T. N. Molostova

Journal volume & issue
Vol. 0, no. 1
pp. 182 – 186

Abstract

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The issues (aspects) of bronchodilator and tocolytic actions of β₂-adrenoceptor agonists are reviewed. The data on short-acting and new long-acting β₂-agonists are presented. It is marked that it is necessary to use long-acting β₂-agonists and glucocorticosteroids concomitantly. Examples of clinical efficacy of locally produced β₂-adrenoceptor agonist salbutamol hemisuccinate in various dosage forms used as a bronchodilator for treatment of bronchopulmonary diseases, and also as a tocolytic for habitual noncarrying of pregnancy are given.

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