Symptomatic focal nodular hyperplasia during pregnancy: A case report

Valerie Byrnes, MD; Andrés Cárdenas, MMSc, MD; Nezam Afdhal, MD; Douglas Hanto, PhD, MD

Annals of Hepatology (Jan 2004)

Symptomatic focal nodular hyperplasia during pregnancy: A case report

Valerie Byrnes, MD,
Andrés Cárdenas, MMSc, MD,
Nezam Afdhal, MD,
Douglas Hanto, PhD, MD

Affiliations

Valerie Byrnes, MD: Department of Gastroenterology and Hepatology and Department of Hepatobiliary Surgery and Liver Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
Andrés Cárdenas, MMSc, MD: Department of Gastroenterology and Hepatology and Department of Hepatobiliary Surgery and Liver Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.; Address for correspondence:
Nezam Afdhal, MD: Department of Gastroenterology and Hepatology and Department of Hepatobiliary Surgery and Liver Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
Douglas Hanto, PhD, MD: Department of Gastroenterology and Hepatology and Department of Hepatobiliary Surgery and Liver Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.

Journal volume & issue: Vol. 3, no. 1
pp. 35 – 37

Abstract

Read online

A 30-year-old woman presented with hepatomegaly and an audible hepatic bruit at 24 weeks gestation. Non-contrast MRI demonstrated an exophytic 12.6 x 7.8 x 12.8 cm mass arising from the right lobe of the liver with a central scar, suggestive of focal nodular hyperplasia (FNH). Conservative management included monthly abdominal ultrasound examinations until the time of delivery, to assess growth of the mass and monitor for risk of rupture. Seven weeks post partum the patient experienced severe right upper quadrant pain. A CT angiogram of the liver demonstrated a stable mass with no evidence of bleed or rupture and multiple hypervascular masses throughout the liver. Surgical resection of the dominant lesion was performed. Histological examination of the lesion confirmed FNH. The patient is now 22 months post surgery with radiographic evidence of stable multifocalFNH.

Published in Annals of Hepatology

ISSN: 1665-2681 (Print); 2659-5982 (Online)
Publisher: Elsevier
Country of publisher: Spain
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine
Website: https://www.journals.elsevier.com/annals-of-hepatology

About the journal

Abstract

Keywords