Pathogens (Aug 2023)

Efficiency of Experimental Formulation Containing <i>Duddingtonia flagrans</i> and <i>Pochonia chlamydosporia</i> against <i>Moniezia expansa</i> Eggs

  • Giancarlo Bomfim Ribeiro,
  • Ially de Almeida Moura,
  • André Ricardo e Silva,
  • Jackson Victor de Araújo,
  • Caio Márcio de Oliveira Monteiro,
  • Júlia dos Santos Fonseca,
  • Ana Patrícia David de Oliveira,
  • Wendell Marcelo de Souza Perinotto

DOI
https://doi.org/10.3390/pathogens12081028
Journal volume & issue
Vol. 12, no. 8
p. 1028

Abstract

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This study aimed to evaluate the effectiveness of the experimental formulation containing chlamydospores of Duddingtonia flagrans and Pochonia chlamydosporia fungi, against Moniezia expansa. Two experiments were carried out. The first experiment evaluated the in vitro efficacy using 1 g of the experimental formulation (V1) added to 100 M. expansa eggs and the control (V2) (without the fungal formulation). Intact eggs or eggs with alterations were counted in order to evaluate their effectiveness. The second experiment evaluated the action of the fungal formulation on M. expansa eggs after passing through the gastrointestinal tract of goats. Three groups were identified as B1, B2, and B3, which received 1.0, 1.5 g of experimental fungal formulation, and placebo, respectively. In experiment 1, all the eggs in V1 were subjected to the predatory action of fungi, while in V2, the eggs remained intact. In experiment 2, the reduction of eggs in groups B1 and B2 were 49% and 57% 24 h after ingestion, 60% and 63% 48 h after, and 48% and 58% 72 h after. The predatory capacity against M. expansa eggs shown in the tests demonstrated that experimental fungal formulation has the potential to be used on integrated helminth control programs.

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