Comparative efficacy and safety of clarithromycin in the treatment of bacterial sinusitis

Abstract

Inflammatory pathology of the nasal cavity and paranasal sinuses is one of the major challenges in otorhinolaryngology today. Among patients hospitalized in ENT units, the incidence of inflammatory diseases of the paranasal sinuses is up to 36%. Modern macrolides (especially clarithromycin and azithromycin) are among the most common antibiotics in outpatient practice. The revival of interest in macrolide antibiotics was conditioned by an increase in their clinical value in infectious pathology of intracellular pathogens where macrolides showed a unique activity.

Keywords

• риносинусит
• воспалительные заболевания околоносовых пазух
• макролиды
• rhinosinusitis
• inflammatory diseases of the paranasal sinuses
• macrolides