Mean Platelet Volume to Platelet Count Ratio Predicts Left Atrial Stasis in Patients with Non-Valvular Atrial Fibrillation

Abstract

Xiaoyan Liu, Shandong Yu, Tuo Liang, Lizhu Chen, Heping Zhang Department of Cardiology, Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Heping Zhang, Department of Cardiology, Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, No. 95, Yongan Road, Beijing, 100050, People’s Republic of China, Tel [phone], Email [email protected]: The mean platelet volume to platelet count ratio (MPV/PC) has been investigated in the diagnosis, prognosis and risk stratification in several diseases. However, the predictive role of MPV/PC in left atrial stasis (LAS) of non-valvular atrial fibrillation (NVAF) patients remains unknown.Methods: A total of 217 consecutive NVAF patients undergoing transesophageal echocardiogram (TEE) evaluation were retrospectively enrolled. The demographic, clinical, admission laboratory and TEE data were extracted and analyzed. Patients were categorized into those with or without LAS. The associations between the MPV/PC ratio and LAS were assessed by multivariate logistic regression analysis.Results: There were 24.9% (n = 54) patients with LAS according to TEE. Compared with patients without LAS, the MPV/PC ratio was significantly higher in those with LAS (5.6± 1.6 vs 4.8± 1.0, P 34mL/m2 (all P 34mL/m2 patients.Graphical Abstract: Keywords: non-valvular atrial fibrillation, mean platelet volume to platelet count ratio, left atrial appendage thrombus, spontaneous echo contrast

Keywords

• non-valvular atrial fibrillation
• mean platelet volume to platelet count ratio
• left atrial appendage thrombus
• spontaneous echo contrast.