Nature Communications (May 2022)

Differential regulation of alternative promoters emerges from unified kinetics of enhancer-promoter interaction

  • Jingyao Wang,
  • Shihe Zhang,
  • Hongfang Lu,
  • Heng Xu

DOI
https://doi.org/10.1038/s41467-022-30315-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

Read online

Alternative promoters differ in their expression patterns, whose mechanisms are not well understood. Here the authors show that alternative promoters of a Drosophila embryonic gene hunchback are regulated by different action modes of two enhancers.