Communications Biology (Jun 2022)

Capturing additional genetic risk from family history for improved polygenic risk prediction

Tianyuan Lu,
Vincenzo Forgetta,
J. Brent Richards,
Celia M. T. Greenwood

Affiliations

Tianyuan Lu: Lady Davis Institute for Medical Research, Jewish General Hospital
Vincenzo Forgetta: Lady Davis Institute for Medical Research, Jewish General Hospital
J. Brent Richards: Lady Davis Institute for Medical Research, Jewish General Hospital
Celia M. T. Greenwood: Lady Davis Institute for Medical Research, Jewish General Hospital

DOI: https://doi.org/10.1038/s42003-022-03532-4
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

A computational method improves prediction of complex traits by incorporating genetic information from polygenic risk scores with family history.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal