Immunology Team-Based Learning: Basic Concepts in Immunology

Abstract

Abstract Introduction This resource is a team-based learning (TBL) exercise to help learners understand the basic principles of innate and adaptive immunity as well as effector mechanisms of adaptive immunity and how to apply those principles in experimental settings. Methods Specific topics introduced in this module include cell types and tissue organization; functions of B cells and T cell subsets; humoral and cell-mediated immunity; lymphocyte activation; and antigen presentation. Learners are also introduced to the historical development of current concepts in immunology regarding the use of antisera to cell surface molecules as markers for lymphocyte subsets, B-T lymphocyte interactions during humoral responses, and antigen recognition by B and T cells. Results Student satisfaction with this TBL is very high, as assessed by course evaluations over the past 3 years. Students say that TBL helps them keep up with material and helps them prepare for exams. Student performance on high-stakes exams reveals modest improvements in overall scores. Discussion These materials have been used in teaching immunology to biomedical science graduate students in a course entitled “Principles of Immunology.” This material is also suitable for use in teaching immunology to medical students, dental students, residents, and fellows.

Keywords

• TBL
• Team-Based Learning
• Antibody
• Plasma Cells
• B-Cells
• Lymphocytes