Journal for ImmunoTherapy of Cancer (Nov 2023)
1403-A PTPN2/N1 inhibitor ABBV-CLS-484 unleashes potent anti-tumor immunity
- Wei Qiu,
- Qi Sun,
- Yi Yang,
- Chirag Patel,
- Meng Sun,
- Yue Liu,
- Kyle Halliwill,
- Sarah Kim,
- Rebecca Mathew,
- Jennifer M Frost,
- Jennifer A Roth,
- Domenick Kennedy,
- Robert T Manguso,
- Kathleen B Yates,
- Hakimeh Ebrahimi-Nik,
- Christina K Baumgartner,
- Arvin Iracheta-Vellve,
- Keith M Hamel,
- Kira Olander,
- Thomas GR Davis,
- Kathleen A McGuire,
- Geoff T Halvorsen,
- Omar I Avila,
- Ashwin V Kammula,
- Audrey J Muscato,
- Prasanthi Geda,
- Kelly Klinge,
- Zhaoming Xiong,
- Ryan Duggan,
- Liang Mu,
- Mitchell D Yeary,
- James C Patti,
- Tyler M Balon,
- Carey Backus,
- Angeline Chen,
- Kenton Longenecker,
- Joseph Klahn,
- Cara Hrusch,
- Navasona Krishnan,
- Charles W Hutchins,
- Jacqueline Aguado,
- Marinka Bulic,
- Payal Tiwari,
- Kayla J Colvin,
- Cun Lan Chuong,
- Ian C Kohnle,
- Matthew G Rees,
- Andrew Boghossian,
- Melissa Ronan,
- Meng-Ju Wu,
- Debattama R Sen,
- Gabriel K Griffin,
- Nabeel El-Bardeesy,
- Patricia Trusk,
- Joshua H Decker,
- Stacey Fossey,
- Marcia N Paddock,
- Elliot P Farney,
- Clay Beauregard,
- Philip R Kym
Affiliations
- Wei Qiu
- 4AbbVie Inc., North Chicago, IL, USA
- Qi Sun
- 1 Department of Nutrition, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA
- Yi Yang
- 1Biocytogen Pharmaceuticals (Beijing) Co., Ltd., Beijing, China
- Chirag Patel
- 7Calico Life Sciences, South San Francisco, CA, USA
- Meng Sun
- 7Calico Life Sciences, South San Francisco, CA, USA
- Yue Liu
- 7Calico Life Sciences, South San Francisco, CA, USA
- Kyle Halliwill
- 8AbbVie, San Bruno, CA, USA
- Sarah Kim
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Rebecca Mathew
- 10AbbVie Inc., South San Franscisco, CA, USA
- Jennifer M Frost
- 4AbbVie Inc., North Chicago, IL, USA
- Jennifer A Roth
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Domenick Kennedy
- 4AbbVie Inc., North Chicago, IL, USA
- Robert T Manguso
- 3Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA
- Kathleen B Yates
- 3Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA
- Hakimeh Ebrahimi-Nik
- 3Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA
- Christina K Baumgartner
- 4AbbVie Inc., North Chicago, IL, USA
- Arvin Iracheta-Vellve
- 5AstraZeneca, Wellesley, MA, USA
- Keith M Hamel
- 4AbbVie Inc., North Chicago, IL, USA
- Kira Olander
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Thomas GR Davis
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Kathleen A McGuire
- 4AbbVie Inc., North Chicago, IL, USA
- Geoff T Halvorsen
- 4AbbVie Inc., North Chicago, IL, USA
- Omar I Avila
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Ashwin V Kammula
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Audrey J Muscato
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Prasanthi Geda
- 9Bristol Myers Squibb, Summit, NJ, USA
- Kelly Klinge
- 4AbbVie Inc., North Chicago, IL, USA
- Zhaoming Xiong
- 4AbbVie Inc., North Chicago, IL, USA
- Ryan Duggan
- 4AbbVie Inc., North Chicago, IL, USA
- Liang Mu
- 4AbbVie Inc., North Chicago, IL, USA
- Mitchell D Yeary
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- James C Patti
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Tyler M Balon
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Carey Backus
- 10AbbVie Inc., South San Franscisco, CA, USA
- Angeline Chen
- 4AbbVie Inc., North Chicago, IL, USA
- Kenton Longenecker
- 4AbbVie Inc., North Chicago, IL, USA
- Joseph Klahn
- 11AbbVie, Elk Grove Village, IL, USA
- Cara Hrusch
- 4AbbVie Inc., North Chicago, IL, USA
- Navasona Krishnan
- 4AbbVie Inc., North Chicago, IL, USA
- Charles W Hutchins
- 4AbbVie Inc., North Chicago, IL, USA
- Jacqueline Aguado
- 4AbbVie Inc., North Chicago, IL, USA
- Marinka Bulic
- 4AbbVie Inc., North Chicago, IL, USA
- Payal Tiwari
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Kayla J Colvin
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Cun Lan Chuong
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Ian C Kohnle
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Matthew G Rees
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Andrew Boghossian
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Melissa Ronan
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Meng-Ju Wu
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Debattama R Sen
- 3Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA
- Gabriel K Griffin
- 6Broad Institute of MIT and Harvard, Cambridge, MA, USA
- Nabeel El-Bardeesy
- 3Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA
- Patricia Trusk
- 4AbbVie Inc., North Chicago, IL, USA
- Joshua H Decker
- 4AbbVie Inc., North Chicago, IL, USA
- Stacey Fossey
- 4AbbVie Inc., North Chicago, IL, USA
- Marcia N Paddock
- 7Calico Life Sciences, South San Francisco, CA, USA
- Elliot P Farney
- 4AbbVie Inc., North Chicago, IL, USA
- Clay Beauregard
- 7Calico Life Sciences, South San Francisco, CA, USA
- Philip R Kym
- 4AbbVie Inc., North Chicago, IL, USA
- DOI
- https://doi.org/10.1136/jitc-2023-SITC2023.1403-A
- Journal volume & issue
-
Vol. 11,
no. Suppl 2
Abstract
No abstracts available.