Nature Communications (Jun 2021)

Association between confirmed congenital Zika infection at birth and outcomes up to 3 years of life

  • Najeh Hcini,
  • Yaovi Kugbe,
  • Zo Hasina Linah Rafalimanana,
  • Véronique Lambert,
  • Meredith Mathieu,
  • Gabriel Carles,
  • David Baud,
  • Alice Panchaud,
  • Léo Pomar

DOI
https://doi.org/10.1038/s41467-021-23468-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Here, using diagnostic tools in a longitudinal cohort of ZIKV-infected pregnant women of the French Guiana Western Hospital Center (CHOG) and their infants, the authors investigate the long term neuropathological effects of congenital infection, finding that a laboratory confirmed congenital ZIKV infection at birth is associated with higher risks of adverse neurological outcomes up to three years of life.