Cells (Aug 2018)

Revisiting Centrioles in Nematodes—Historic Findings and Current Topics

  • Anna Schwarz,
  • Prabhu Sankaralingam,
  • Kevin F. O’Connell,
  • Thomas Müller-Reichert

DOI
https://doi.org/10.3390/cells7080101
Journal volume & issue
Vol. 7, no. 8
p. 101

Abstract

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Theodor Boveri is considered as the “father” of centrosome biology. Boveri’s fundamental findings have laid the groundwork for decades of research on centrosomes. Here, we briefly review his early work on centrosomes and his first description of the centriole. Mainly focusing on centriole structure, duplication, and centriole assembly factors in C. elegans, we will highlight the role of this model in studying germ line centrosomes in nematodes. Last but not least, we will point to future directions of the C. elegans centrosome field.

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