Comparison of different types of molar volume equations for the validity and applicability in a ternary (carbamazepine+alizarin+methanol) solution system and study of the corresponding molecular interactions

Abstract

In this work, the molecular interaction between the carbamazepine and alizarin in methanol has been represented in terms of limiting apparent molar volumes and viscosity coefficients. Before further proceeding, the validity and applicability of the calculation of apparent molar volumes have also been checked by considering the available five types of frequently used equations, where the required modifications have proposed by the addition of hypothetical mass and concentration of the solute. After that, the limiting apparent molar volume and viscosity coefficients have been calculated using Masson equation and Jones–Dole equation respectively to predict and cross-check the interactions occurring between the molecules in ternary system. The equation marked with (1) has been found the best-fit equation, and the carbamazepine and alizarin in methanol are strongly bound (фV o = 23104 m3 mol-1 and B = 18.10 kg mol-1) to each other at the concentration 0.003 mol kg-1. The results have been interpreted in favour of the solute–cosolute interactions, which is dominant over the solute–solute and cosolute–cosolute interactions. The interpretations have been discussed with the help of intermolecular forces and noncovalent interactions.

Keywords

• dihydroxyanthraquinone
• dibenzoazepine-based compound
• limiting apparent molar volume
• viscosity b-coefficient
• solute-solvent and solute-solute interactions