Nature Communications (May 2018)

Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus

  • Sakiko Honjoh,
  • Shuntaro Sasai,
  • Shannon S Schiereck,
  • Hirotaka Nagai,
  • Giulio Tononi,
  • Chiara Cirelli

DOI
https://doi.org/10.1038/s41467-018-04497-x
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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The ventromedial thalamus (VM) is thought to control cortical arousal through its diffuse projections to cortex. Here the authors record and manipulate the activity of calbindin1-positive matrix cells in VM and show that they bidirectionally regulate the sleep-wake transition.