A Case of Atypical Cleft Hand - Reported with Ontogenetic Review

Abstract

An asymptomatic atypical U shaped cleft hand has been found in a 21-year-old lady attending OPD. On digital skiagram it was found that central digits were absent with remnants of bases of the metacarpals, which have fused with the carpal bones. Moreover, the scaphoid and trapezium had fused to form a single mass. There was no other anomaly in other limbs, so far searched for. An endeavor has been made to explain the anomaly with ontogenetic review.

Keywords

• apical ectodermal ridge
• early differentiation model
• homeobox (hox) gene
• lobster-claw hand
• progressive zone model