Molecules (Oct 2017)

Facile and Green Synthesis of Saturated Cyclic Amines

  • Arruje Hameed,
  • Sadia Javed,
  • Razia Noreen,
  • Tayyaba Huma,
  • Sarosh Iqbal,
  • Huma Umbreen,
  • Tahsin Gulzar,
  • Tahir Farooq

DOI
https://doi.org/10.3390/molecules22101691
Journal volume & issue
Vol. 22, no. 10
p. 1691

Abstract

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Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes and azocanes. This review highlights some facile and green synthetic routes for the synthesis of unsubstituted, multisubstituted and highly functionalized saturated cyclic amines including one-pot, microwave assisted, metal-free, solvent-free and in aqueous media.

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