Phenolic constituents from twigs of Aleurites fordii and their biological activities

Abstract

Three new neolignan glycosides (1–3), a new phenolic glycoside (15), and a new cyanoglycoside (16) were isolated and characterized from the twigs of Aleurites fordii together with 14 known analogues (4–14 and 17–19). The structural elucidation of the new compounds was performed through the analysis of their NMR, HRMS, and ECD spectra and by chemical methods. All isolated compounds were tested for their antineuroinflammatory and neuroprotective activities.

Keywords

• aleurites fordii
• antineuroinflammation
• euphorbiaceae
• neolignan glycoside
• neuroprotective activity
• phenolic compound