Association of occlusal support with type 2 diabetes: A community-based study

Dongxin Da; Dongxin Da; Suyu Ge; Suyu Ge; Hao Zhang; Hao Zhang; Xiaoli Zeng; Xiaoli Zeng; Yiwei Jiang; Yiwei Jiang; Jin Yu; Jin Yu; Huning Wang; Huning Wang; Wanqing Wu; Wanqing Wu; Wanqing Wu; Zhenxu Xiao; Zhenxu Xiao; Zhenxu Xiao; Xiaoniu Liang; Xiaoniu Liang; Xiaoniu Liang; Ding Ding; Ding Ding; Ding Ding; Ying Zhang; Ying Zhang

doi:10.3389/fendo.2022.934274

Frontiers in Endocrinology (Aug 2022)

Association of occlusal support with type 2 diabetes: A community-based study

Dongxin Da,
Dongxin Da,
Suyu Ge,
Suyu Ge,
Hao Zhang,
Hao Zhang,
Xiaoli Zeng,
Xiaoli Zeng,
Yiwei Jiang,
Yiwei Jiang,
Jin Yu,
Jin Yu,
Huning Wang,
Huning Wang,
Wanqing Wu,
Wanqing Wu,
Wanqing Wu,
Zhenxu Xiao,
Zhenxu Xiao,
Zhenxu Xiao,
Xiaoniu Liang,
Xiaoniu Liang,
Xiaoniu Liang,
Ding Ding,
Ding Ding,
Ding Ding,
Ying Zhang,
Ying Zhang

Affiliations

Dongxin Da: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Dongxin Da: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Suyu Ge: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Suyu Ge: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Hao Zhang: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Hao Zhang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Xiaoli Zeng: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Xiaoli Zeng: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Yiwei Jiang: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Yiwei Jiang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Jin Yu: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Jin Yu: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Huning Wang: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Huning Wang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Wanqing Wu: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Wanqing Wu: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Wanqing Wu: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Zhenxu Xiao: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Xiaoniu Liang: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China
Ding Ding: National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China
Ying Zhang: Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China
Ying Zhang: Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China

DOI: https://doi.org/10.3389/fendo.2022.934274
Journal volume & issue: Vol. 13

Abstract

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Occlusal support was proved to be associated with type 2 diabetes. Our aim was to investigate the association between the Eichner index and the prevalence of type 2 diabetes. We included 715 participants with oral health examinations in the Shanghai Aging Study. The occlusal support status was determined by the number of functional occlusal support areas and Eichner index classifications. Those with fasting plasma glucose ≥126 mg/dL and/or hemoglobin A1c ≥6.5% and/or current medications for type 2 diabetes with relevant medical history were diagnosed with type 2 diabetes. Multiple logistic regression models were used to analyze the relationship between occlusal support status and type 2 diabetes. The average age of 715 participants was 73.74 ± 6.49 years old. There were 84 diabetics with 1.71 occlusal supporting areas on average. Seven hundred and fifteen participants were divided into 3 groups according to Eichner classifications: Eichner group A with 4 occlusal functional areas, Eichner group B with 1-3 occlusal functional areas or 0 area with anterior occlusal contact, and Eichner group C with no functional occlusal contact. Blood glucose level was significantly lower in participants of Eichner group A compared to those in group B or C. The ordinal logistic regression showed more occlusal supporting areas were significantly associated with less type 2 diabetes cases with an Odds Ratio(OR) of 0.253(95%CI 0.108-0.594) after adjusting covariates. Participants in Eichner group A had a significantly much lower OR of 0.078 for type 2 diabetes (95%CI 0.009-0.694) compared to those in Eichner group C after adjustment. The number of functional occlusal support areas might be inversely related to the blood glucose level and the prevalence of type 2 diabetes.

Published in Frontiers in Endocrinology

ISSN: 1664-2392 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.frontiersin.org/journals/endocrinology

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