Some applications of deep eutectic solvents in alkylation of heterocyclic compounds: A review of the past 10 years

Abstract

This mini-review encapsulates the latest findings (past 10 years) in the field of the deep eutectic solvents (DESs) application in the alkylation/arylation of different heterocyclic compounds. These solvents have been developed to fulfill the green chemistry concept demands and have been proven excellent for the application in various fields. This review describes their application in different types of alkylation, C-, N-, O- and S-alkylation. P-alkylation has not yet been published within this scope. Not only have the authors in this study proven that DESs could be successfully applied for this specific type of reaction, but they have also offered an excellent insight into the mechanisms of their action.

Keywords

• deep eutectic solvents
• alkylation
• heterocyclic compounds
• green chemistry