Postoperative hypoxia and length of intensive care unit stay after cardiac surgery: the underweight paradox?

Abstract

ObjectiveCardiac operations with cardiopulmonary bypass can be associated with postoperative lung dysfunction. The present study investigates the incidence of postoperative hypoxia after cardiac surgery, its relationship with the length of intensive care unit stay, and the role of body mass index in determining postoperative hypoxia and intensive care unit length of stay.DesignSingle-center, retrospective study.SettingUniversity Hospital. Patients. Adult patients (N = 5,023) who underwent cardiac surgery with CPB.InterventionsNone.Measurements and main resultsAccording to the body mass index, patients were attributed to six classes, and obesity was defined as a body mass index >30. POH was defined as a PaO2/FiO2 ratio ConclusionsObese patients are at higher risk for postoperative hypoxia, but this leads to a prolonged intensive care unit stay only for moderate-morbid obese patients. Obese patients are partially protected against the deleterious effects of hemodilution and transfusions. Underweight patients present the "paradox" of a better lung gas exchange but a longer intensive care unit stay. This is probably due to a higher severity of their cardiac disease.