Nature Communications (Aug 2022)
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
- Justine Y. Hansen,
- Golia Shafiei,
- Jacob W. Vogel,
- Kelly Smart,
- Carrie E. Bearden,
- Martine Hoogman,
- Barbara Franke,
- Daan van Rooij,
- Jan Buitelaar,
- Carrie R. McDonald,
- Sanjay M. Sisodiya,
- Lianne Schmaal,
- Dick J. Veltman,
- Odile A. van den Heuvel,
- Dan J. Stein,
- Theo G. M. van Erp,
- Christopher R. K. Ching,
- Ole A. Andreassen,
- Tomas Hajek,
- Nils Opel,
- Gemma Modinos,
- André Aleman,
- Ysbrand van der Werf,
- Neda Jahanshad,
- Sophia I. Thomopoulos,
- Paul M. Thompson,
- Richard E. Carson,
- Alain Dagher,
- Bratislav Misic
Affiliations
- Justine Y. Hansen
- McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University
- Golia Shafiei
- McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University
- Jacob W. Vogel
- Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania
- Kelly Smart
- Department of Radiology and Biomedical Imaging, Yale School of Medicine
- Carrie E. Bearden
- Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, University of California
- Martine Hoogman
- Departments of Psychiatry and Human Genetics, Radboud University Medical Center
- Barbara Franke
- Departments of Psychiatry and Human Genetics, Radboud University Medical Center
- Daan van Rooij
- Donders Institute for Brain, Cognition and Behavior, Radboud University
- Jan Buitelaar
- Donders Institute for Brain, Cognition and Behavior, Radboud University
- Carrie R. McDonald
- Department of Psychiatry, University of California San Diego
- Sanjay M. Sisodiya
- Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology
- Lianne Schmaal
- Centre for Youth Mental Health, The University of Melbourne
- Dick J. Veltman
- Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience
- Odile A. van den Heuvel
- Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience
- Dan J. Stein
- SA MRC Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry & Neuroscience Institute, University of Cape Town
- Theo G. M. van Erp
- Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, & Center for the Neurobiology of Leaning and Memory, University of California Irvine, 309 Qureshey Research Lab
- Christopher R. K. Ching
- Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California
- Ole A. Andreassen
- NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital
- Tomas Hajek
- Department of Psychiatry, Dalhousie University
- Nils Opel
- Institute of Translational Psychiatry, University of Münster, Münster, Germany & Department of Psychiatry, Jena University Hospital/Friedrich-Schiller-University Jena
- Gemma Modinos
- Department of Psychosis Studies & MRC Centre for Neurodevelopmental Disorders, King’s College London
- André Aleman
- Department of Biomedical Sciences of Cells and Systems, University of Groningen
- Ysbrand van der Werf
- Department of Anatomy & Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience
- Neda Jahanshad
- Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California
- Sophia I. Thomopoulos
- Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California
- Paul M. Thompson
- Keck School of Medicine, Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California
- Richard E. Carson
- Department of Radiology and Biomedical Imaging, Yale School of Medicine
- Alain Dagher
- McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University
- Bratislav Misic
- McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University
- DOI
- https://doi.org/10.1038/s41467-022-32420-y
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
Changes to structural and functional connectivity can give rise to neurodegeneration and neurodevelopmental diseases. Here the authors investigate molecular and connectomic patterns in 13 different neurological, psychiatric and neurodevelopmental diseases from the ENIGMA consortium.
