Regulation of Apoptosis by the Bcl-2 Family of Proteins: Field on a Brink

Abstract

Apoptosis, a form of programmed cell death, is a highly regulated process critical for tissue development, homeostasis, and pathogenesis of various diseases [...]

Keywords

• apoptosis
• mitochondrial outer membrane permeabilization
• protein–membrane interactions
• Bcl-2 proteins as therapeutic targets
• cancer