Nature Communications (May 2018)

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

  • Jorge C. G. Blanco,
  • Lioubov M. Pletneva,
  • Lori McGinnes-Cullen,
  • Raymonde O. Otoa,
  • Mira C. Patel,
  • Lurds R. Fernando,
  • Marina S. Boukhvalova,
  • Trudy G. Morrison

DOI
https://doi.org/10.1038/s41467-018-04216-6
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

Read online

RSV infection is a major cause of bronchiolitis in infants and maternal vaccination is a potential preventive option. Here, Blanco et al. show efficacy of a Newcastle disease virus-based virus-like particle vaccine candidate in naive and pre-exposed cotton rat dams and their offspring.