Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

Jens Hillengass; Sofia Ayyaz; Kerstin Kilk; Marc-André Weber; Thomas Hielscher; Rajiv Shah; Dirk Hose; Stefan Delorme; Hartmut Goldschmidt; Kai Neben

doi:10.3324/haematol.2012.065359

Haematologica (Nov 2012)

Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

Jens Hillengass,
Sofia Ayyaz,
Kerstin Kilk,
Marc-André Weber,
Thomas Hielscher,
Rajiv Shah,
Dirk Hose,
Stefan Delorme,
Hartmut Goldschmidt,
Kai Neben

Affiliations

Jens Hillengass: Department of Internal Medicine V, University of Heidelberg;Department of Radiology, German Cancer Research Centre, Heidelberg
Sofia Ayyaz: Department of Internal Medicine V, University of Heidelberg
Kerstin Kilk: Department of Diagnostic and Interventional Radiology, University of Heidelberg
Marc-André Weber: Department of Diagnostic and Interventional Radiology, University of Heidelberg
Thomas Hielscher: Department of Biostatistics, German Cancer Research Centre, Heidelberg
Rajiv Shah: Department of Radiology, German Cancer Research Centre, Heidelberg
Dirk Hose: Department of Internal Medicine V, University of Heidelberg
Stefan Delorme: Department of Radiology, German Cancer Research Centre, Heidelberg
Hartmut Goldschmidt: Department of Internal Medicine V, University of Heidelberg;National Centre for Tumour Diseases, Heidelberg, Germany
Kai Neben: Department of Internal Medicine V, University of Heidelberg

DOI: https://doi.org/10.3324/haematol.2012.065359
Journal volume & issue: Vol. 97, no. 11

Abstract

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In multiple myeloma, focal lesions, as well as diffuse and variegated infiltration patterns, can be detected by magnetic resonance imaging. In the current study, we compared treatment response in 100 myeloma patients with changes in infiltration patterns in whole body magnetic resonance imaging before and after autologous stem cell transplantation. We found an agreement between serological response and changes in imaging (P

Published in Haematologica

ISSN: 0390-6078 (Print); 1592-8721 (Online)
Publisher: Ferrata Storti Foundation
Country of publisher: Italy
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: http://www.haematologica.org

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