A Case of Granulomatosis with Polyangiitis in Pregnancy

Abstract

Granulomatosis with polyangiitis, a rare autoimmune disease affecting organs such as the respiratory system, kidneys, and lungs, poses unique challenges in pregnancy. A 25-year-old woman with chronic liver disease, vasculitis, protein C and S deficiency, hypothyroidism, and gestational diabetes presented at 24 weeks gestation with shortness of breath, fever, and vomiting. Her thrombocytopenia was managed with transfusions, and regular prenatal ultrasounds were conducted. At 36 weeks, an elective cesarean delivered a healthy 2.4 kg baby. This case highlights the critical role of multidisciplinary care in achieving favorable outcomes in complex pregnancies affected by granulomatosis with polyangiitis.

Keywords

• Granulomatosis with Polyangiitis
• Wegener’ Granulomatosis
• Granulomatous Vasculitis
• ANCA-Associated Vasculitis
• Pregnancy