Iodine-131 S values for use in organ dose estimation of Korean patients in radioiodine therapy

Yeon Soo Yeom; Bangho Shin; Chansoo Choi; Haegin Han; Chan Hyeong Kim

Nuclear Engineering and Technology (Feb 2022)

Iodine-131 S values for use in organ dose estimation of Korean patients in radioiodine therapy

Yeon Soo Yeom,
Bangho Shin,
Chansoo Choi,
Haegin Han,
Chan Hyeong Kim

Affiliations

Yeon Soo Yeom: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, 20850, USA; Department of Radiation Convergence Engineering, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon-do, 26493, South Korea; Corresponding author. 1 Yonseidae-gil, Wonju, Gangwon-do, 26493, South Korea.
Bangho Shin: Department of Nuclear Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea
Chansoo Choi: Department of Nuclear Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea
Haegin Han: Department of Nuclear Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea
Chan Hyeong Kim: Department of Nuclear Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea

Journal volume & issue: Vol. 54, no. 2
pp. 689 – 700

Abstract

Read online

In the present study, iodine-131 S values (rT ← thyroid) were calculated for 30 target organs and tissues using the most recently developed Korean reference computational phantoms. The calculated S values were then compared with those of the International Commission on Radiological Protection (ICRP) reference computational phantoms to investigate the dosimetric impact of the Korean S values against those of the ICRP reference phantoms. The results showed significant differences in the S values due to the different anatomical/morphological characteristics between the Korean and ICRP reference phantoms. Most target organs/tissues showed that the S values of the Korean reference phantoms are lower than those of the ICRP reference phantoms, by up to about 4 times (male spleen and female thymus). Exceptionally, three target organs/tissues (gonads, thyroid, and extrathoracic region) showed that the S values of the Korean reference phantoms are greater, by 1.5–3.7 times. We expect that the S values calculated in the present study will be beneficially used to estimate organ/tissue doses of Korean patients under radioiodine therapy.

Published in Nuclear Engineering and Technology

ISSN: 1738-5733 (Print)
Publisher: Elsevier
Country of publisher: Korea, Republic of
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Nuclear engineering. Atomic power
Website: http://www.journals.elsevier.com/nuclear-engineering-and-technology

About the journal

Abstract

Keywords