Prognostic value of EIF5A2 in solid tumors: A meta-analysis and bioinformatics analysis

Fang Jianwen; Yu Tianze; Jiang Xiaocong; Lu Yuexin; Shang Xi; Shen Haixing; Lu Yue; Zheng Jingyan; Fu Peifen

doi:10.1515/med-2024-0962

Open Medicine (May 2024)

Prognostic value of EIF5A2 in solid tumors: A meta-analysis and bioinformatics analysis

Fang Jianwen,
Yu Tianze,
Jiang Xiaocong,
Lu Yuexin,
Shang Xi,
Shen Haixing,
Lu Yue,
Zheng Jingyan,
Fu Peifen

Affiliations

Fang Jianwen: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
Yu Tianze: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
Jiang Xiaocong: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
Lu Yuexin: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
Shang Xi: Department of Breast and Thyroid Surgery, Taizhou Hospital, Zhejiang University, Taizhou, Zhejiang, 318000, China
Shen Haixing: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
Lu Yue: Department of Breast and Thyroid Surgery, First Affiliated Hospital of Huzhou University, Huzhou, 313000, Zhejiang, China
Zheng Jingyan: Department of Breast and Thyroid Surgery, Lishui People’s Hospital, The Six Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, 323000, China
Fu Peifen: Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China

DOI: https://doi.org/10.1515/med-2024-0962
Journal volume & issue: Vol. 19, no. 1
pp. 101 – 9

Abstract

Read online

In cancer biology, the aberrant overexpression of eukaryotic translation initiation factor 5A2 (EIF5A2) has been correlative with an ominous prognosis, thereby underscoring its pivotal role in fostering metastatic progression. Consequently, EIF5A2 has garnered significant attention as a compelling prognostic biomarker for various malignancies. Our research endeavors were thus aimed at elucidating the utility and significance of EIF5A2 as a robust indicator of cancer outcome prediction.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

Keywords