The dose accumulation and the impact of deformable image registration on dose reporting parameters in a moving patient undergoing proton radiotherapy

Abstract

Potential changes in patient anatomy during proton radiotherapy may lead to a deviation of the delivered dose. A dose estimate can be computed through a deformable image registration (DIR) driven dose accumulation. The present study evaluates the accumulated dose uncertainties in a patient subject to an inadvertent breathing associated motion.

Keywords

• proton therapy
• adaptive therapy
• mcnp6
• dose distribution measurement
• monte-carlo
• dose homogeneity
• image registration