Department of Commitment Management, Directorate of Health Affairs in the Eastern Province, Dammam 31176, Saudi Arabia
Wadha A. Alfouzan
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait
Ali M. Al-Bahar
Department of Laboratory, Dhahran Long Term Care Hospital, Dhahran 34257, Saudi Arabia
Mohammed Garout
Department of Community Medicine and Health Care for Pilgrims, Faculty of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia
Muhammad A. Halwani
Department of Medical Microbiology, Faculty of Medicine, Al Baha University, Al Baha 4781, Saudi Arabia
Hawra Albayat
Infectious Disease Department, King Saud Medical City, Riyadh 7790, Saudi Arabia
Norah B. Almutairi
Infectious Disease Department, King Saud Medical City, Riyadh 7790, Saudi Arabia
Mohammed Alsaeed
Infectious Disease Division, Department of Medicine, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia
Jeehan H. Alestad
Immunology and Infectious Microbiology Department, University of Glasgow, Glasgow G1 1XQ, UK
Maha A. Al-Mozaini
Immunocompromsised Host Research Section, Department of Infection and Immunity, King Faisal, Specialist Hospital and Research Centre, Riyadh 11564, Saudi Arabia
Tala M. Al Ashgar
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia
Sultan Alotaibi
Molecular Microbiology Department, King Fahad Medical City, Riyadh 11525, Saudi Arabia
Abdulmonem A. Abuzaid
Medical Microbiology Department, Security Forces Hospital Programme, Dammam 32314, Saudi Arabia
Yahya Aldawood
Clinical Laboratory Science Department, Mohammed Al-Mana College for Medical Sciences, Dammam 34222, Saudi Arabia
Abdulmonem A. Alsaleh
Clinical Laboratory Science Department, Mohammed Al-Mana College for Medical Sciences, Dammam 34222, Saudi Arabia
Hani M. Al-Afghani
Laboratory Department, Security Forces Hospital, Makkah 24269, Saudi Arabia
Jaffar A. Altowaileb
Microbiology Laboratory, Laboratory Department, Qatif Central Hospital, Qatif 32654, Saudi Arabia
Abeer N. Alshukairi
College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia
Kovy Arteaga-Livias
Escuela de Medicina-Filial Ica, Universidad Privada San Juan Bautista, Ica 11000, Peru
Kirnpal Kaur Banga Singh
Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia
Mohd Imran
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, Saudi Arabia
The purpose of this review is to give an up-to-date, thorough, and timely overview of monkeypox (Mpox), a severe infectious viral disease. Furthermore, this review provides an up-to-date treatment option for Mpox. The monkeypox virus (MPXV) has remained the most virulent poxvirus for humans since the elimination of smallpox approximately 41 years ago, with distribution mainly in central and west Africa. Mpox in humans is a zoonotically transferred disease that results in symptoms like those of smallpox. It had spread throughout west and central Africa when it was first diagnosed in the Republic of Congo in 1970. Mpox has become a major threat to global health security, necessitating a quick response by virologists, veterinarians, public health professionals, doctors, and researchers to create high-efficiency diagnostic tests, vaccinations, antivirals, and other infection control techniques. The emergence of epidemics outside of Africa emphasizes the disease’s global significance. A better understanding of Mpox’s dynamic epidemiology may be attained by increased surveillance and identification of cases.