Radiology Case Reports (Jul 2022)

Giant malignant sacrococcygeal germ cell tumor in a newborn: A rare case report

  • Carmela Brillantino,
  • Maria Elena Errico,
  • Rocco Minelli,
  • Giovanni Gaglione,
  • Pietro Pirisi,
  • Antonio Rossi,
  • Biagio Francesco Menna,
  • Marika Santarsiere,
  • Mariateresa Rumolo,
  • Eugenio Rossi

Journal volume & issue
Vol. 17, no. 7
pp. 2416 – 2423

Abstract

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Malignant germ cell tumors constitute about 3%-4% of all neoplasms occurring before the age of 15. They arise in the ovaries, the testes, and in several other locations, including the lower back, the chest, the brain, and the abdomen. In infants and young children, the sacrococcygeal region is the most common site for extragonadal germ cell tumors, and teratomas account for the vast majority of sacrococcygeal germ cell tumors. Neonatal sacrococcygeal teratomas are usually benign and rarely they may contain a malignant component that is predominantly a yolk sac tumor. In this article, we describe a rare case of a male newborn with a giant sacrococcygeal mixed germ cell tumor composed of grade 3 immature teratoma and malignant yolk sac elements.

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