Research progress on Robinia pseudoacacia preparation in treating malignant tumors of digestive system

Abstract

The morbidity and mortality rates of digestive system tumors rank relatively high among malignant tumors. At present, the treatment methods of advanced tumors are mainly surgery in combination with chemotherapy, radiotherapy, immunotherapy and molecular targeted therapy, etc. Due to severe adverse reactions, traditional radiotherapy and chemotherapy cannot yield satisfactory efficacy. In recent years, the therapeutic value of Chinese herbal medicine for malignant tumors has attracted widespread attention. As a traditional Chinese medicine, Robinia pseudoacacia is widely applied to treat multiple types of malignant tumors of digestive system. The anti-tumor mechanisms of Robinia pseudoacacia include inducing tumor cell apoptosis, delaying tumor angiogenesis, inhibiting tumor cell proliferation, invasion and metastasis and reversing tumor drug resistance. At present, it has been widely utilized as an adjuvant anti-tumors drug in clinical practice. In this review, the mechanism of Robinia pseudoacacia preparation against malignant digestive system tumors was unraveled, providing novel ideas and methods for clinical treatment of malignant digestive system tumors.

Keywords

• |robinia pseudoacacia preparation|digestive system|malignant tumor|traditional chinese medicine|mechanism of tumors