Nature Communications (Dec 2021)
Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome
Abstract
There is currently no disease-modifying treatment for Parkinson’s disease, a common neurodegenerative disorder. Here, the authors use genetic variation associated with gene and protein expression to find putative drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome.