Place cells are more strongly tied to landmarks in deep than in superficial CA1

Abstract

Environmental cues affect the way mouse hippocampal place cells respond, but whether this information is integrated versus segregated in distinct hippocampal cell populations is unclear. Here, the authors record neuronal activity in the hippocampus of mice on a treadmill enriched with visual-tactile landmarks, and show anatomically segregated cells with variable ties to the cues.