Rore: robust and efficient antioxidant protein classification via a novel dimensionality reduction strategy based on learning of fewer features

Abstract

Abstract In protein identification, researchers increasingly aim to achieve efficient classification using fewer features. While many feature selection methods effectively reduce the number of model features, they often cause information loss caused by merely selecting or discarding features, which limits classifier performance. To address this issue, we present Rore, an algorithm based on a feature-dimensionality reduction strategy. By mapping the original features to a latent space, Rore retains all relevant feature information while using fewer representations of the latent features. This approach significantly preserves the original information and overcomes the information loss problem associated with previous feature selection. Through extensive experimental validation and analysis, Rore demonstrated excellent performance on an antioxidant protein dataset, achieving an accuracy of 95.88% and MCC of 91.78%, using vectors including only 15 features. The Rore algorithm is available online at http://112.124.26.17:8021/Rore .

Keywords

• Dimensionality reduction
• Robust feature
• Protein classifier
• Protein sequence