Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation

Amit Jethanandani; Amit Jethanandani; Maria K. Gule-Monroe; Melissa Chen; Jason M. Johnson

doi:10.3389/fonc.2019.00373

Frontiers in Oncology (May 2019)

Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation

Amit Jethanandani,
Amit Jethanandani,
Maria K. Gule-Monroe,
Melissa Chen,
Jason M. Johnson

Affiliations

Amit Jethanandani: Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, United States
Amit Jethanandani: University of Tennessee Health Science Center, College of Medicine, Memphis, TN, United States
Maria K. Gule-Monroe: Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States
Melissa Chen: Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States
Jason M. Johnson: Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States

DOI: https://doi.org/10.3389/fonc.2019.00373
Journal volume & issue: Vol. 9

Abstract

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Distant metastatic disease from gliomas is extremely rare. We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. The presence of an H3F3A mutation in these patients may indicate further work-up to include intensive staging examination.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

About the journal

Abstract

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