Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa

Abstract

Human sera from the United States, Thailand, and sub-Saharan Africa and chimpanzee sera were tested for neutralizing antibodies to 3 chimpanzee adenoviruses. Antibodies were more common in humans residing in sub-Saharan Africa than in humans living in the United States or Thailand. This finding suggests cross-species transmission of chimpanzee adenoviruses.

Keywords

• Neutralizing antibodies
• prevalence
• chimpanzee adenovirus
• chimpanzee-to-human transmission
• Africa
• vaccine