Induced pluripotent stem cell line (ZZUNEUi011-A) derived from peripheral blood mononuclear cells (PBMCs) of a healthy 27-year-old female individual

Wanrong Fu; Mengyu Wang; Yangyang Liu; Mengduan Liu; Lu Wang; Liang Hu; Xiaoyan Zhao; Zhongren Ding; Xiaowei Li; Jianzeng Dong

doi:10.1016/j.scr.2020.102139

Stem Cell Research (Jan 2021)

Induced pluripotent stem cell line (ZZUNEUi011-A) derived from peripheral blood mononuclear cells (PBMCs) of a healthy 27-year-old female individual

Wanrong Fu,
Mengyu Wang,
Yangyang Liu,
Mengduan Liu,
Lu Wang,
Liang Hu,
Xiaoyan Zhao,
Zhongren Ding,
Xiaowei Li,
Jianzeng Dong

Affiliations

Wanrong Fu: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Mengyu Wang: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Yangyang Liu: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Mengduan Liu: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Lu Wang: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Liang Hu: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Xiaoyan Zhao: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Zhongren Ding: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China
Xiaowei Li: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China; Corresponding authors at: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jianzeng Dong: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Cardiovascular Institute of Zhengzhou University, Zhengzhou 450052, China; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Centre for Cardiovascular Diseases, No. 2 Beijing Anzhen Road, Chaoyang District, Beijing 100029, China; Corresponding authors at: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

DOI: https://doi.org/10.1016/j.scr.2020.102139
Journal volume & issue: Vol. 50
p. 102139

Abstract

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In this study, we report a human induced pluripotent stem cell (iPSC) line from a healthy 27-year-old female individual using non-integrative Sendai viral reprogramming technology. The cell line expresses stemness markers, exhibits a normal female karyotype, and can differentiate into three germ layers in vivo. This iPSC line from a healthy individual provides a control group for studying disease mechanisms, drug screening, and toxicity testing.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.sciencedirect.com/journal/stem-cell-research

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