Translational Neuroscience (Aug 2019)

Heart rate variability and vagus nerve stimulation in epilepsy patients

  • Constantinescu Victor,
  • Matei Daniela,
  • Constantinescu Irina,
  • Cuciureanu Dan Iulian

DOI
https://doi.org/10.1515/tnsci-2019-0036
Journal volume & issue
Vol. 10, no. 1
pp. 223 – 232

Abstract

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Vagus nerve stimulation (VNS) exerts a cortical modulating effect through its diffuse projections, especially involving cerebral structures related to autonomic regulation. The influence of VNS on cardiovascular autonomic function in drug-resistant epilepsy patients is still debated. We aimed to evaluate the impact of VNS on cardiovascular autonomic function in drug-resistant epilepsy patients, after three months of neurostimulation, using the heart rate variability (HRV) analysis.

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