Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours

Yordi J. van de Vegte; M. Abdullah Said; Michiel Rienstra; Pim van der Harst; Niek Verweij

doi:10.1038/s41467-020-15553-w

Nature Communications (Apr 2020)

Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours

Yordi J. van de Vegte,
M. Abdullah Said,
Michiel Rienstra,
Pim van der Harst,
Niek Verweij

Affiliations

Yordi J. van de Vegte: Department of Cardiology, University of Groningen, University Medical Center Groningen
M. Abdullah Said: Department of Cardiology, University of Groningen, University Medical Center Groningen
Michiel Rienstra: Department of Cardiology, University of Groningen, University Medical Center Groningen
Pim van der Harst: Department of Cardiology, University of Groningen, University Medical Center Groningen
Niek Verweij: Department of Cardiology, University of Groningen, University Medical Center Groningen

DOI: https://doi.org/10.1038/s41467-020-15553-w
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

Read online

Epidemiological studies have shown an association between sedentary behaviours and cardiovascular disease risk. Here, van de Vegte et al. perform GWAS for self-reported sedentary behaviours (TV watching, computer use, driving) and Mendelian randomization analyses to explore potential causal relationships with coronary artery disease.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal