Saudi Journal of Kidney Diseases and Transplantation (Jan 2008)

A transplant recipient with a mixed germ-cell ovarian tumor

  • Ketata Hafed,
  • Bouacida Mahdi,
  • Bouhlel Abdelkader,
  • Sahnoun Ahmed,
  • Bahloul Ali,
  • Yaich Soumaya,
  • Hachicha Jamil,
  • Mhiri Mohamed

Journal volume & issue
Vol. 19, no. 6
pp. 973 – 975


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Immunosuppressed renal transplant recipients seem to be at significantly increased risk of developing neoplasms comparatively to nonimmunosuppressed individuals. A history of malignancy exposes the patient to a high risk for relapse after transplantation. We present a trans-plant recipient with a history of an ovarian mixed germ-cell tumor, with choriocarcinoma com-ponent, which was treated seven years prior to transplantation. After three years of follow-up, there was no evidence of tumor relapse. To our knowledge, there is no report of such case in the English literature. Regarding our case report and patients with a history of ovarian germ-cell neoplasm, waiting time before transplantation must take into consideration the stage of the tumor, its prognosis, the proportion of different tumor components, and the overall prognosis of the patient if transplantation is withheld.