Drug Design, Development and Therapy (Feb 2017)

Profile of mirabegron in the treatment of overactive bladder: place in therapy

  • Sharaf A,
  • Hashim H

Journal volume & issue
Vol. Volume11
pp. 463 – 467

Abstract

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Ala’a Sharaf, Hashim Hashim Female and Functional Urology Unit, Bristol Urological Institute, Bristol, UK Abstract: Mirabegron is a relatively new drug introduced to treat overactive bladder syndrome. It can be used either on its own or as part of a combination. This drug has been extensively studied, with a good number of Phase II and Phase III trials showing promising outcomes. These studies show that mirabegron is an effective, well-tolerated drug, which could have some adverse effects of concern. In this review, we look at the trials on mirabegron, as well as its pharmacokinetics, mechanism of action, and side effects as documented in the literature. Keywords: mirabegron, overactive bladder disorder, antimuscarinics

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