Сибирский онкологический журнал (Nov 2017)

Rational approaches to the therapy of nosocomial infections caused by gram-positive microorganisms in cancer p

  • V. V. Aginova,
  • N. V. Dmitrieva,
  • Z. V. Grigorievskaya,
  • I. N. Petukhova,
  • N. S. Bagirova,
  • I. V. Tereshchenko,
  • I. А. Klyuchnikova

DOI
https://doi.org/10.21294/1814-4861-2017-16-5-12-17
Journal volume & issue
Vol. 16, no. 5
pp. 12 – 17

Abstract

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Nosocomial infections caused by gram-positive organisms, including Staphylococcus aureus and enterococci (Enterococcus faecium and Enterococcus faecalis) are steadily increasing in almost all clinics around the world. Cancer patients have a higher risk of hospital-acquired infections than non-cancer patients. Cancer patients are immunosuppressed due to increased use of broad-spectrum antibiotics and chemotherapy drugs, radiation therapy, surgery and use of steroids. This paper presents an analysis of resistance of gram-positive bacterial pathogens to antimicrobial agents to determine treatment strategy for cancer patients.

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