Annals of Internal Medicine: Clinical Cases (May 2023)

Lisinopril-Induced Burning Mouth Syndrome

  • Nithya Sridhar,
  • Zehra Tosur

DOI
https://doi.org/10.7326/aimcc.2022.1103
Journal volume & issue
Vol. 2, no. 5

Abstract

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Burning mouth syndrome (BMS) is defined as an uncomfortable burning sensation in the mouth and/or tongue in the absence of any oral mucosa lesions, sores, or other abnormalities. We describe a case in which a patient had a burning sensation in her mouth for several years with no identifiable cause. Two weeks after her primary care physician switched her lisinopril to another antihypertensive medication, she noted significant improvement in her symptoms and an improved quality of life. It is imperative for physicians to recognize angiotensin-converting enzyme inhibitors, specifically lisinopril, as a possible cause of burning mouth syndrome in symptomatic patients.