Nature Communications (Apr 2018)

Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers

  • Stephanie Lauback,
  • Kara R. Mattioli,
  • Alexander E. Marras,
  • Maxim Armstrong,
  • Thomas P. Rudibaugh,
  • Ratnasingham Sooryakumar,
  • Carlos E. Castro

DOI
https://doi.org/10.1038/s41467-018-03601-5
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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DNA molecular machines hold promise for biological nanotechnology, but how to actuate them in a fast and programmable manner remains challenging. Here, Lauback et al. demonstrate direct manipulation of DNA origami assemblies via a micrometer-long stiff mechanical lever controlled by a magnetic field.