КардиоСоматика (Jun 2017)
Psychoemotional status and neuroendocrine changes in patients with hypertension and obesity according to the level of physical activity
Abstract
Aim. To study psychoemotional status and serum cortisol changes in patients with arterial hypertension (AH) and obesity, depending on the level of physical activity. Material and methods. 76 male patients with AH stage I and II were examined. Group 1 consisted of 36 patients with AH and obesity, group 2 - 40 hypertensive patients without obesity. Serum cortisol level was determined by enzyme-linked immunosorbent assay. To access level of psycho-emotional strain in patients PSM-25 scale was used. The level of reactive and personal anxiety was measured using a Spielberger-Khanin questionnaire. To assess physical activity a brief international physical activity questionnaire (IPAQ) was used. Results. Each group was divided into two subgroups depending on the level of physical activity. According to results of psychological questionnaires physically inactive patients showed significantly higher levels of psychoemotional stress and serum cortisol concentrations as compared to physically active patients. There was an inverse correlation between the level of physical activity with reactive anxiety in group 1 (r=-0.35; p=0.04), and between physical activity with personal anxiety (r=-0.36; p=0.02) and psychoemotional strain in group 2 (r=-0.42; p=0.006). There also was an inverse association between the level of physical activity with systolic (group 1 - r=-0.52; p=0.001; group 2 - r=-0.52; p=0.0006) and diastolic (group 2 - r=-0.45; p=0.004) blood pressure. All groups showed an inverse relationship between physical activity level and serum cortisol concentration that was statistically significant in group 2 (r=-0.36; p=0.04). Conclusion. Our results support the hypothesis that regular physical activity confers resilience by oftimizing physiological and neuroendocrine responses and acts as a buffer against stressors.
