Single-cell sequencing deconvolutes cellular responses to exercise in human skeletal muscle

Alen Lovrić; Ali Rassolie; Seher Alam; Mirko Mandić; Amarjit Saini; Mikael Altun; Rodrigo Fernandez-Gonzalo; Thomas Gustafsson; Eric Rullman

doi:10.1038/s42003-022-04088-z

Communications Biology (Oct 2022)

Single-cell sequencing deconvolutes cellular responses to exercise in human skeletal muscle

Alen Lovrić,
Ali Rassolie,
Seher Alam,
Mirko Mandić,
Amarjit Saini,
Mikael Altun,
Rodrigo Fernandez-Gonzalo,
Thomas Gustafsson,
Eric Rullman

Affiliations

Alen Lovrić: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Ali Rassolie: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Seher Alam: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Mirko Mandić: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Amarjit Saini: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Mikael Altun: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Rodrigo Fernandez-Gonzalo: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Thomas Gustafsson: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge
Eric Rullman: Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet Huddinge

DOI: https://doi.org/10.1038/s42003-022-04088-z
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 14

Abstract

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Single-cell RNA-sequencing of human skeletal muscle before and after exercise highlights how physical activity changes the composition and transcriptomic profile of muscle tissue.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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