Nature Communications (Jan 2023)

Natural oxidase-mimicking copper-organic frameworks for targeted identification of ascorbate in sensitive sweat sensing

  • Zhengyun Wang,
  • Yuchen Huang,
  • Kunqi Xu,
  • Yanyu Zhong,
  • Chaohui He,
  • Lipei Jiang,
  • Jiankang Sun,
  • Zhuang Rao,
  • Jiannan Zhu,
  • Jing Huang,
  • Fei Xiao,
  • Hongfang Liu,
  • Bao Yu Xia

DOI
https://doi.org/10.1038/s41467-022-35721-4
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 9

Abstract

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Sweat sensors are important in personalized healthcare using natural oxidase to target biomolecules but these reactions are susceptible to external interference. Here, the authors report tryptophan- and histidine-treated copper metal-organic frameworks which show highly selective activity for ascorbate oxidation and can serve as an efficient ascorbate oxidase-mimicking material in sensitive sweat sensors.